Clinical Experience with New Antiepileptic Drugs: Antiepileptic Drugs in Europe

New antiepileptic drugs – an

The last ten years of the 20th century is called in neuroscience “decade of the brain”. This period has brought many new antiepileptic drugs (AEDs) to the practising physician. New AEDs include: vigabatrin, lamotrigine, topiramate, tiagabine, gabapentin, oxcarbazepine, levetiracetam and zonisamide (not registered in Poland). The development of these drugs was under the current epilepsy theory (...

New antiepileptic drugs. II. Clinical use.

The new antiepileptic drugs: clinical applications.

In the past decade, 8 new antiepileptic drugs have been approved for use in the United States, offering many new treatment options to patients with epilepsy. With expanding use of these newer agents, primary care clinicians are challenged with understanding the roles that each new agent plays in the treatment of patients with epilepsy as well as possible interactions with other pharmacological ...

Experience with new antiepileptic drugs among Indians with refractory epilepsy

Objectives: We assessed the comparative efficacy and tolerability of topiramate (TPM), lamotrigine (LTG), gabapentin (GBP) and clobazam (CLB) with an aim to formulate clinical guidelines while initiating treatment with new anti-epileptic drugs (AEDs). Methods: A prospective open label, nonrandomized, add-on study was conducted on 203 Indian patients with seizures refractory to conventional AEDs...

P 146: The Best New Antiepileptic Drugs to Prevent Orofacial Malformations as Side Effects of Antiepileptic Drugs

Mothers exposed to Antiepileptic drugs (AEDs) are at high risk to born babies with orofacial malformations such as cleft lips. About 9 percent of congenital abnormalities in babies of mothers with epilepsy relates to orofacial abnormalities. Maintaining safe antiepileptic drugs for millions of mothers with epilepsy is very important. Researches show that new AEDs have less side effects than the...